منابع مشابه
Enzymatic conversion of cyanide to thiocyanate.
T HE minute amounts of thiocyanate normally present in urine, blood and saliva have stimulated the interest of many workers as to the origin of the cyanide and the pattern of conversion of cyanide to thiocyanate. The problem has toxicologic as well as physiologic importance because of the great toxicity of cyanide. The detoxication of cyanide in the animal body was first demonstrated by S. Lang...
متن کاملOxidation of thiocyanate to cyanide catalyzed by hemoglobin.
Thiocyanate ion is oxidized at acid pH by hydrogen peroxide to sulfate and cyanide. The reaction is catalyzed in the erythrocyte by hemoglobin acting as a peroxidase (donor: Hz02 oxidoreductase, EC 1.11.1.7). Kinetic studies show thiocyanate ion fulfdls criteria for a substrate for the peroxidase. The peroxidase activity is enhanced by haptoglobin and inhibited by azide, aminotriazole, fluoride...
متن کاملCyanide and thiocyanate concentrations following sodium nitroprusside infusion in man.
Twenty-six patients, receiving an infusion of sodium nitroprusside (SNP) during surgery, had considerable increases in both red cell and plasma cyanide concentration, but only small changes in plasma thiocyanate concentration. There was a linear relationship between both plasma and RBC cyanide concentrations and the total dose of SNP. The expired cyanide concentration followed the changes in th...
متن کاملAccumulation of cyanide and thiocyanate in haemodialysis patients.
BACKGROUND Cyanide is a toxic agent, and its detoxification product, thiocyanate, may be a major pathogenetic substance in uraemia. Recent studies examining the myeloperoxidase(MPO)/thiocyanate system have suggested a link between thiocyanate and atherosclerosis. However, inaccuracies in conventional assays for cyanide and thiocyanate have limited the understanding of their metabolism in haemod...
متن کاملMetagenomic data of free cyanide and thiocyanate degrading bacterial communities
The data presented in this article contains the bacterial community structure of the free cyanide (CN-) and thiocyanate (SCN-) degrading organisms that were isolated from electroplating wastewater and synthetic SCN- containing wastewater. PCR amplification of the 16S rRNA V1-V3 regions was undertaken using the 27F and 518R oligonucleotide primers following the metacommunity DNA extraction proce...
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ژورنال
عنوان ژورنال: Clinical Toxicology
سال: 1980
ISSN: 0009-9309
DOI: 10.3109/15563658008989929